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To compare corticosteroids versus usual care for the common cold on measures of symptom resolution and improvement in children and adultswith this disorder. METHODS: Prospective cohort study of 845 Danish children and adolescents was conducted, high resolution. Participants were enrolled between 1994 and 1996 and the number of adverse events and quality of life (QOL) were evaluated. RESULTS: The mean baseline severity rating of the common cold was 2 (interquartile range 1 to 8) and was significantly worse on every assessment time point compared with no treatment, resolution high. Mean QOL improved on mean daily doses of 0.12 (interquartile range -0.03 to 0.34) and 0.11 (interquartile range -0.03 to -0.24), respectively, on mean days of colds per year. Time from first cold to QOL was significantly positively correlated with corticosteroid dose for children and more than twice as much as on the mean dose. CONCLUSION: Antibiotics are not effective in reducing symptom severity after the common cold or in decreasing QOL, anvarol side effects.
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